The term methadone mainly used for pain management. The people who are addicted to various narcotics such as heroin, opium are treated by methadone.
It is very much safe and effective when it is prescribed by a doctor or pharmacist. But it has to be kept in mind that the amount of using methadone should be appropriate.
No drug in this world comes without the side effects of methadone. But without knowing the side effects of Methadone drugs, we will not be able to counter those complications.
For getting optimal results, the patient involves ideal counseling and social support. Methadone is also used to relieve pain, heart attacks, trauma, and surgery.
How methadone works
Methadone works almost in the same way as morphine and other opioid drugs works. They work as an agonist. After binding with the receptors, they exert their effect. These opioid receptors transmit pain.
When the drug gets attached to the receptors, the pain gets reduced because the pain cannot then transmit to the brain. They do not treat the underlying cause of pain but only helps the patient to feel better.
Doing this the morphine gives the patient euphoria. Cannot controlled. Which synthetically prepared in different laboratories. Pharmaceutical does not create the euphoretic effect. Because the morphine gets attached with the opioid receptor more quickly than methadone. So the methadone gives their effect slowly. As a result, the euphoretic effect avoided.
Lets know about “what is methadone used for pain”
There are several programs for the treatment of methadone management. Mainly two types of methadone program, which are-
- Maintenance, which is a long term program.
- Withdrawal, which is short term detoxification program.
The way of administering methadone includes injection or tablets. Last years the synthetic methadone is used in the management of chronic cancer and intractable neuropathic pain.
Its also used as an analgesic for the treatment of noncancer pain. Unfortunately, the evidence for its use in the management of neuropathic pain is limited to a few case studies.
The patients should discontinue the use of methadone due to the absence of pain and various intractable. Common side effects of methadone include nervousness, restlessness, sleeping problems, nausea, vomiting, etc.
Dosing of methadone depends on the general age condition and medical status of the patient. It should be noted that methadone may interact with other narcotic pain medications, sedatives, muscle relaxers, other medications that can make us sleepy or slow our breathing.
Taking opioid medicine like methadone during pregnancy may cause life-threatening withdrawal symptoms in the newborn. Apart from its side effects, it changes the way of the brain and nervous system responding to mind so that pain is relieved.
It affects slower than some of the other strong painkillers like morphine. The most advantageous side is that it can block the highness of getting from drugs like codeine, oxycodone.
Overdose symptoms can cause a slow heart rate, fainting weak muscles, small pupils, etc. One of the most critical warnings of using methadone is that it can be having to form so that it should not be taken as more massive dose or over a more extended period.
Here “Side Effects Of Methadone”
There is some number of side effects of methadone, and also things can done to avoid them. We will discuss some of them:
Slow Breathing or hypotension
Slow breathing problems can occur in patients if he is taking methadone. Due to taking medicine, I higher dose than average or the dos increased too quickly. If the patient was taking the medication for a long time, then this problem does not usually arise.
Generally occurs from taking an overdose of this drug. If the patient is feeling extremely tired as like not getting enough sleep, dizzy, nauseous, and short of breath, he needs to see a doctor immediately. Sometimes the patient takes so much of the medication that it causes the patient to go in a state that he does not feel anything and does not get aroused. At these type of time, he must take to the doctor immediately.
People who take on these type of opioid medications sometimes feel like they have not been feeling enough sleep. They often say things like “ I am not feeling like myself” . After taking these medications, one should avoid doing any hard work or works that might be requiring attention. Like driving, swimming. Alcohol or other sedatives should keep out of reach of the patients unless they specially prescribed. Usually, it takes around two days to get back to the normal state.
A common side effect of pain medication is constipation. People who take this medication suffers from the illness. This side effect can manage by taking some preventive measures:
- Taking a lot of water every day.
- Do labor work as much as possible.
- Maintain a routine to attempt fecal movement.
- Eat plenty of fruits and vegetables.
- Foods which are rich with fibers should take because fibrous food helps in the fetal movement.
Even without these, some laxatives and fecal softeners can prescribe to the patients. Stool softeners can help the fecal to move out of the body. They soften the stool by adding water to the feces. When water softener, it runs out of the body smoothly. A stimulant or laxative works by stimulating the movement of bowel through the body.
Untreated bowled movement can cause blockage of the bowel, and if no stool come out within three days, the physician should consulted.
Addiction, Tolerance, and dependence
Highly addictive medication. Without taking this medication regularly. It causes euphoria to patients who are not suffering from pain. And using it without a prescription causes addiction to this drug.
Also, if the physician does not regulate the drug, it will cause drug tolerance and dependency on the patients.
Nausea and vomiting
This medication can cause nausea with or without vomiting side effect. This feeling can make the patient suffer from uneasiness for quite a long time. Taking this medication on an empty stomach or a full stomach can cause a different result. Can help the patient get a better feeling.
Uncommon side effects
These are some less common side effects of methadone:
- Serotonin syndrome
This medication can, in rare cases cause an increase in the level of serotonin, which leads to serotonin syndrome. Agitation, diarrhea, shivering are the main symptoms of this disease.
- Adrenal insufficiency
Inadequate function of the adrenal gland is the leading cause of this disease. You can show after one month of taking this medication.is also a sporadic case.
- An allergic reaction
also an uncommon side effect. But it can seen in patients.
The unborn child can affect by the effect of this medication. If a mother takes the methadone during pregnancy, the child may be born too small or early.
Methadone is a highly effective drug, and this should take very carefully. Without a prescription, this should not take at all.From the overall description above methadone as unique and complex pharmacology which has a significant oral bioavailability, a gradual onset of action and generally long-acting.
The formations of methadone are essentially bioequivalent. Though methadone contributed to many side effects, the main concerns of using methadone are the unpredictable half-life and the associated risk of delayed overdose.